Coming off a bye week, the Buffalo Bills (9-2) are set to host the San Francisco 49ers (5-6) at Highmark Stadium in Week 13, aiming to build on their six-game winning streak.
Buffalo ’s last outing saw Josh Allen deliver a stellar performance, including a decisive 26-yard touchdown run to edge the Kansas City Chiefs, 21-20, in Week 11. That victory handed the defending Super Bowl champions their first loss of the season.
Allen’s MVP campaign is gaining momentum. With 23 total touchdowns (18 passing) and only seven turnovers this season, he has shed his reputation for inconsistency. Trusting his teammates and executing under pressure, Allen continues to solidify his role as one of the NFL's premier quarterbacks.
Week 13 presents new challenges in terms of "the unknown mystery'' as Allen faces the 49ers for just the second time in his career. The first matchup saw Allen and the Bills emerge victorious 34-24. San Francisco, despite making a Super Bowl appearance last season, has struggled in 2024, currently sitting at the bottom of the NFC West. The 49ers may also be without starting quarterback Brock Purdy, further complicating their chances against the red-hot Bills.
Buffalo has benefited from contributions across the roster, with 11 different players catching touchdowns from Allen this season. Running back James Cook has also been a standout, reaching a career-high 10 touchdowns through 10 games.
A win would bolster Buffalo’s grip on the AFC East and keep the team firmly in the mix for the AFC's top playoff seed. However, the Bills must avoid complacency against a 49ers squad eager to salvage their season.
With San Francisco’s defense still capable of creating disruptions and the Bills striving to maintain their balanced attack, this matchup could serve as a critical test of Buffalo’s postseason readiness as they approach the final stretch of the regular season.
This article first appeared on Athlon Sports and was syndicated with permission.
